Mississippi scored twice on wild pitches in a three-run eighth inning and the Rebels won their first national baseball title, sweeping Oklahoma in the College World Series finals with a 4-2 victory.
The Rebels became the eighth national champion since 2009 to come out of the Southeastern Conference.
The trophy will stay in the Magnolia State for a second straight year. Mississippi State won last year.
Ole Miss benefited from a runner interference call that took a run away from Oklahoma in the sixth inning.
It also overcame a spectacular pitching performance by Cade Horton, who set a CWS finals record with 13 strikeouts.