Latavius Murray scored on a 2-yard touchdown run late in the fourth quarter to help the Denver Broncos snap a four-game losing streak by beating the Jacksonville Jaguars 21-17 at Wembley Stadium.
Russell Wilson led two go-ahead scoring drives in the second half on his return from a hamstring injury.
The late score gave Murray a touchdown for two different teams this month in London.
He ran for a score for New Orleans earlier this month at Tottenham Hotspur Stadium.