Juwan Gary scored 14 points and each Nebraska starter scored in double figures and the Cornhuskers ran away from Iowa early and went on to a 66-50 win.
C.J. Wilcher scored 13 points, Sam Griesel 12 and Emmanuel Bandoumel and Derrick Walker each scored 10 for Nebraska which snapped a three-game losing streak.
Kris Murray, in his first return to the lineup since missing four games due to injury, scored 17 points and grabbed eight rebounds for Iowa.